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Mouse Anti-SEPSECS Recombinant Antibody (CBXS-2165) (CBMAB-S4928-CQ)

This product is a mouse antibody that recognizes SEPSECS. The antibody CBXS-2165 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all SEPSECS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2165
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase
Introduction
The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).
Entrez Gene ID
51091
UniProt ID
Q9HD40
Alternative Names
Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase; Soluble Liver Antigen/Liver Pancreas Antigen; TRNA(Ser/Sec)-Associated Antigenic Protein; UGA Suppressor TRNA-Associated Protein; Liver-Pancreas Antigen; Soluble Liver Antigen; SLA/LP Autoantigen; SLA-P35; SLA; LP; O-Phosphoseryl-TRNA(Sec) Selenium Transferase;
Function
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Biological Process
Biological Process selenocysteine incorporationISS:HGNC-UCL
Biological Process selenocysteinyl-tRNA(Sec) biosynthetic processIEA:UniProtKB-UniPathway
Cellular Location
Cytoplasm
Involvement in disease
Pontocerebellar hypoplasia 2D (PCH2D):
A disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound intellectual disability, spasticity, and variable seizures.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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