Mouse Anti-SEPSECS Recombinant Antibody (EP-1) (CBMAB-H3807-FY)

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Basic Information

Host Animal
Mouse
Clone
EP-1
Application
IHC-Fr, IHC-P
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase
Introduction
The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).
Entrez Gene ID
UniProt ID
Alternative Names
Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase; Soluble Liver Antigen/Liver Pancreas Antigen; TRNA(Ser/Sec)-Associated Antigenic Protein; UGA Suppressor TRNA-Associated Protein; Liver-Pancreas Antigen; Soluble Liver Antigen; SLA/LP Autoantigen; SLA-P35; SLA; LP; O-Phosphoseryl-TRNA(Sec) Selenium Transferase
Function
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Biological Process
Biological Process selenocysteine incorporationISS:HGNC-UCL
Biological Process selenocysteinyl-tRNA(Sec) biosynthetic processIEA:UniProtKB-UniPathway
Cellular Location
Cytoplasm
Involvement in disease
Pontocerebellar hypoplasia 2D (PCH2D):
A disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound intellectual disability, spasticity, and variable seizures.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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