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Mouse Anti-SERTAD1 Recombinant Antibody (3H4) (CBMAB-A8010-LY)

The product is antibody recognizes SERTAD1. The antibody 3H4 immunoassay techniques such as: WB, ELISA.
See all SERTAD1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3H4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SERTAD1 (AAH02670, 1 a.a. ~ 236 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SERTA domain containing 1
Entrez Gene ID
29950
UniProt ID
Q9UHV2
Alternative Names
SEI1; TRIP-Br1
Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Biological Process
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process regulation of cyclin-dependent protein serine/threonine kinase activityManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
nucleus
sarcoplasm
PTM
Polyubiquitinated, which promotes proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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