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Mouse Anti-SERTAD1 Recombinant Antibody (CBFYC-3112) (CBMAB-C3189-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-3112
Antibody Isotype
IgG1
Application
ELISA, WB, IF

Basic Information

Immunogen
Recognizes human Cdk4
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SERTA domain containing 1
Introduction
SERTAD1 (SERTA Domain Containing 1) is a Protein Coding gene.
Entrez Gene ID
29950
UniProt ID
Q9UHV2
Alternative Names
SERTA Domain Containing 1; Transcriptional Regulator Interacting With The PHD-Bromodomain 1; CDK4-Binding Protein P34SEI1; CDK4-Binding Protein P34SEI; TRIP-Br1; SEI-1; SEI1; SERTA Domain-Containing Protein 1
Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Biological Process
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process regulation of cyclin-dependent protein serine/threonine kinase activityManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
nucleus
sarcoplasm
PTM
Polyubiquitinated, which promotes proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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