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Mouse Anti-SERTAD1 (AA 1-20) Recombinant Antibody (CBFYC-3113) (CBMAB-C3190-FY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Pig, Rat
Clone
CBFYC-3113
Antibody Isotype
IgG1, k
Application
IF, IP, WB

Basic Information

Immunogen
Recombinant cdk4 protein. Cellular Localization: Nuclear and cyotplasmic. Epitope: aa1-20
Specificity
Human, Mouse, Pig, Rat
Antibody Isotype
IgG1, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 0.2% BSA
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-20

Target

Full Name
SERTA domain containing 1
Introduction
SERTAD1 (SERTA Domain Containing 1) is a Protein Coding gene.
Entrez Gene ID
Human29950
Mouse55942
Rat361526
Pig100624989
UniProt ID
HumanQ9UHV2
MouseQ9JL10
RatQ6P771
PigI3L6L7
Alternative Names
SERTA Domain Containing 1; Transcriptional Regulator Interacting With The PHD-Bromodomain 1; CDK4-Binding Protein P34SEI1; CDK4-Binding Protein P34SEI; TRIP-Br1; SEI-1; SEI1; SERTA Domain-Containing Protein 1
Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Biological Process
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process regulation of cyclin-dependent protein serine/threonine kinase activityManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
nucleus
sarcoplasm
PTM
Polyubiquitinated, which promotes proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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