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Mouse Anti-SGK2 Recombinant Antibody (2F6) (CBMAB-A8063-LY)

The product is antibody recognizes SGK2. The antibody 2F6 immunoassay techniques such as: WB, ELISA.
See all SGK2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
2F6
Antibody Isotype
IgG3, κ
Application
WB, ELISA

Basic Information

Immunogen
SGK2 (AAH65511, 293 a.a. ~ 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human, Mouse
Antibody Isotype
IgG3, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SGK2, Serine/Threonine Kinase 2
Introduction
This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Two alternate transcripts encoding two different isoforms have been described. [provided by RefSeq]
Entrez Gene ID
Human10110
Mouse27219
UniProt ID
HumanQ9HBY8
MouseQ9QZS5
Alternative Names
H-SGK2; dJ138B7.2
Function
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na+ channels: SCNN1A/ENAC, K+ channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase.
Biological Process
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of transporter activityManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of cell growthManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process regulation of cell population proliferationManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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