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SGK2

This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Full Name
SGK2, Serine/Threonine Kinase 2
Function
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na+ channels: SCNN1A/ENAC, K+ channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase.
Biological Process
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of transporter activityManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of cell growthManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process regulation of cell population proliferationManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Nucleus
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Anti-SGK2 antibodies

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Mouse Anti-SGK2 Recombinant Antibody (CBXS-3392) (CBMAB-S6126-CQ)

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Target: SGK2
Host: Mouse
Specificity: Human
Clone: CBXS-3392
Application*: E, IF, WB
Datasheet SDS

Rabbit Anti-SGK2 Recombinant Antibody (D7G1) (CBMAB-CP2410-LY)

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Target: SGK2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D7G1
Application*: WB
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (7C7) (CBMAB-A8068-LY)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7C7
Application*: WB, E
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (7A6) (CBMAB-A8067-LY)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7A6
Application*: WB, E
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (3D2) (CBMAB-A8065-LY)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D2
Application*: WB, E
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (2F6) (CBMAB-A8063-LY)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse
Clone: 2F6
Application*: WB, E
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (1G11) (CBMAB-A8062-LY)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: 1G11
Application*: WB, E
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (1A7) (CBMAB-A8061-LY)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 1A7
Application*: WB, E
Datasheet SDS

SGK2 Matched Antibody Pair (1088) (APMAB-1088LY)

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Target: SGK2
Specificity: Human
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (CBXS-3166) (CBMAB-S5908-CQ)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBXS-3166
Application*: E, WB
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (CBXS-3046) (CBMAB-S5792-CQ)

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Target: SGK2
Host: Mouse
Specificity: Human
Clone: CBXS-3046
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (CBXS-2677) (CBMAB-S5429-CQ)

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Target: SGK2
Host: Mouse
Specificity: Human
Clone: CBXS-2677
Application*: E, WB
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (CBXS-0334) (CBMAB-S3305-CQ)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-0334
Application*: SE, E, WB, IF
Datasheet SDS

Rabbit Anti-SGK2 Recombinant Antibody (CBXS-5433) (CBMAB-S2644-CQ)

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Target: SGK2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXS-5433
Application*: WB
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (CBXS-4600) (CBMAB-S1840-CQ)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4600
Application*: E, IC, IF, IP, WB
Datasheet SDS

Mouse Anti-SGK2 Recombinant Antibody (CBXS-4153) (CBMAB-S1406-CQ)

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Target: SGK2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4153
Application*: E, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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