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Rabbit Anti-SGK2 Recombinant Antibody (D7G1) (CBMAB-CP2410-LY)

The product is antibody recognizes SGK2. The antibody D7G1 immunoassay techniques such as: WB.
See all SGK2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
D7G1
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys331 of human SGK2 protein.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SGK2, Serine/Threonine Kinase 2
Introduction
This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Entrez Gene ID
Human10110
Mouse27219
Rat171497
UniProt ID
HumanQ9HBY8
MouseQ9QZS5
RatQ8R4U9
Alternative Names
SGK2; Serine/Threonine Kinase 2; Serum/Glucocorticoid Regulated Kinase 2; EC 2.7.11.1; Serum/Glucocorticoid-Regulated Kinase 2; Serine/Threonine-Protein Kinase Sgk2; DJ138B7.2; EC 2.7.11; H-SGK2;
Function
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na+ channels: SCNN1A/ENAC, K+ channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase.
Biological Process
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of transporter activityManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of cell growthManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process regulation of cell population proliferationManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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