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Mouse Anti-SGK2 Recombinant Antibody (CBXS-4600) (CBMAB-S1840-CQ)

This product is a mouse antibody that recognizes SGK2. The antibody CBXS-4600 can be used for immunoassay techniques such as: ELISA, ICC, IF, IP, WB.
See all SGK2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4600
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF, IP, WB

Basic Information

Immunogen
SGK2 (NP_057360, 244 a.a.-344 a.a) full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SGK2, Serine/Threonine Kinase 2
Introduction
This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
10110
UniProt ID
Q9HBY8
Alternative Names
SGK2, Serine/Threonine Kinase 2; Serum/Glucocorticoid Regulated Kinase 2; EC 2.7.11.1; Serum/Glucocorticoid-Regulated Kinase 2; Serine/Threonine-Protein Kinase Sgk2; DJ138B7.2; EC 2.7.11; H-SGK2;
Function
Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na+ channels: SCNN1A/ENAC, K+ channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase.
Biological Process
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of transporter activityManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process regulation of cell growthManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process regulation of cell population proliferationManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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