Mouse Anti-SH2D3C Recombinant Antibody (CBXS-0340) (CBMAB-S3311-CQ)
Compare
Online Inquiry
Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays a role in integrin-mediated cell adhesion through BCAR1-CRK-RAPGEF1 signaling and activation of the small GTPase RAP1 (PubMed:12432078).
Promotes cell migration and invasion through the extracellular matrix (PubMed:20881139).
Required for marginal zone B-cell development and thymus-independent type 2 immune responses (By similarity).
Mediates migration and adhesion of B cells in the splenic marginal zone via promoting hyperphosphorylation of NEDD9/CASL (By similarity).
Plays a role in CXCL13-induced chemotaxis of B-cells (By similarity).
Plays a role in the migration of olfactory sensory neurons (OSNs) into the forebrain and the innervation of the olfactory bulb by the OSN axons during development (By similarity).
Required for the efficient tyrosine phosphorylation of BCAR1 in OSN axons (By similarity).
Isoform 1
Important regulator of chemokine-induced, integrin-mediated T lymphocyte adhesion and migration, acting upstream of RAP1 (By similarity).
Required for tissue-specific adhesion of T lymphocytes to peripheral tissues (By similarity).
Required for basal and CXCL2 stimulated serine-threonine phosphorylation of NEDD9 (By similarity).
May be involved in the regulation of T-cell receptor-mediated IL2 production through the activation of the JNK pathway in T-cells (By similarity).
Isoform 2
May be involved in the BCAR1/CAS-mediated JNK activation pathway.
Biological Process positive regulation of peptidyl-serine phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cell membrane
Cell projection, axon
Cell projection, ruffle membrane
Associated with the membrane when EGF-stimulated (By similarity).
Expressed at the cortical actin ring in B cells (By similarity).
Isoform 1
Cell membrane
Phosphorylated by MAPK/ERK upon T-cell receptor stimulation in T-cells.
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon
$30 eGift Card
Submit a review
Loading...
Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
SH2D3C Matched Antibody Pair (1092) (CAT#: APMAB-1092LY)
Related Products
Mouse Anti-SH2D3C Recombinant Antibody (2B4) (CAT#: CBMAB-A8079-LY)
Mouse Anti-SH2D3C Recombinant Antibody (2G1) (CAT#: CBMAB-A8080-LY)
Mouse Anti-SH2D3C Recombinant Antibody (1B6) (CAT#: CBMAB-A8078-LY)
Mouse Anti-SH2D3C Recombinant Antibody (3C5) (CAT#: CBMAB-A8081-LY)
SH2D3C Matched Antibody Pair (1092) (CAT#: APMAB-1092LY)
Mouse Anti-SH2D3C Recombinant Antibody (3F5) (CAT#: CBMAB-A8083-LY)
Mouse Anti-SH2D3C Recombinant Antibody (2E3) (CAT#: CBMAB-A8077-LY)
Mouse Anti-SH2D3C Recombinant Antibody (CBXS-2845) (CAT#: CBMAB-S5595-CQ)
SH2D3C Matched Antibody Pair (1093) (CAT#: APMAB-1093LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
Online InquiryContact us
