Mouse Anti-SHC3 Recombinant Antibody (CBXS-2711) (CBMAB-S5462-CQ)

Name: Mouse Anti-SHC3 Recombinant Antibody (CBXS-2711)
SKU: CBMAB-S5462-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-2711

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa381-481 from human SHC3 (NP_058544) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SHC (Src homology 2 domain containing) transforming protein 3

Entrez Gene ID

53358

UniProt ID

Q92529

Alternative Names

SHC Adaptor Protein 3; SHC (Src Homology 2 Domain Containing) Transforming Protein 3; SHC-Transforming Protein C; SH2 Domain Protein C3; Neuronal Shc; Protein Rai; N-Shc; NSHC;

Function

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

Biological Process

Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionIEA:InterPro
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytosol
plasma membrane

PTM

Tyrosine phosphorylated.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Mouse Anti-SHC3 Recombinant Antibody (CBWJN-1675) (CAT#: CBMAB-N4260-WJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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