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Mouse Anti-SHC3 Recombinant Antibody (CBXS-2711) (CBMAB-S5462-CQ)

This product is a mouse antibody that recognizes SHC3. The antibody CBXS-2711 can be used for immunoassay techniques such as: ELISA, WB.
See all SHC3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-2711
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa381-481 from human SHC3 (NP_058544) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SHC (Src homology 2 domain containing) transforming protein 3
Entrez Gene ID
53358
UniProt ID
Q92529
Alternative Names
SHC Adaptor Protein 3; SHC (Src Homology 2 Domain Containing) Transforming Protein 3; SHC-Transforming Protein C; SH2 Domain Protein C3; Neuronal Shc; Protein Rai; N-Shc; NSHC;
Function
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Biological Process
Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionIEA:InterPro
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
plasma membrane
PTM
Tyrosine phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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