SHC3

SHC3 (SHC Adaptor Protein 3) is a protein coding gene. Diseases associated with SHC3 include Sarcomatous Intrahepatic Cholangiocarcinoma and Sclerosing Hepatic Carcinoma. Among its related pathways are Focal Adhesion and Endometrial cancer. Gene Ontology annotations related to this gene include protein kinase binding and receptor tyrosine kinase binding. An important paralog of this gene is SHC1.

SHC (Src homology 2 domain containing) transforming protein 3

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionIEA:InterPro
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central

cytosol
plasma membrane

Tyrosine phosphorylated.