SHC3

SHC3 (SHC Adaptor Protein 3) is a protein coding gene. Diseases associated with SHC3 include Sarcomatous Intrahepatic Cholangiocarcinoma and Sclerosing Hepatic Carcinoma. Among its related pathways are Focal Adhesion and Endometrial cancer. Gene Ontology annotations related to this gene include protein kinase binding and receptor tyrosine kinase binding. An important paralog of this gene is SHC1.
Full Name
SHC (Src homology 2 domain containing) transforming protein 3
Function
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Biological Process
Biological Process central nervous system developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process epidermal growth factor receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionIEA:InterPro
Biological Process transmembrane receptor protein tyrosine kinase signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
plasma membrane
PTM
Tyrosine phosphorylated.
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Anti-SHC3 antibodies

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Recombinant Mouse Anti-SHC3 Recombinant Antibody (IF15-E2) (CBMAB-XB1032-YC)

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Target: SHC3
Host: Mouse
Specificity: Human, Mouse
Clone: IF15-E2
Application*: IH, IP, WB
Recombinant Mouse Anti-SHC3 Recombinant Antibody (IF15-E2)
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Mouse Anti-SHC3 Recombinant Antibody (CBXS-2711) (CBMAB-S5462-CQ)

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Target: SHC3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-2711
Application*: E, WB
Mouse Anti-SHC3 Recombinant Antibody (CBXS-2711)
Datasheet SDS

Mouse Anti-SHC3 Recombinant Antibody (CBWJN-1675) (CBMAB-N4260-WJ)

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Target: SHC3
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBWJN-1675
Application*: WB, IF
Mouse Anti-SHC3 Recombinant Antibody (CBWJN-1675)
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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