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Mouse Anti-SHCBP1 Recombinant Antibody (1G8) (CBMAB-A8111-LY)

The product is antibody recognizes SHCBP1. The antibody 1G8 immunoassay techniques such as: WB, ELISA.
See all SHCBP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G8
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
SHCBP1 (NP_079021.2, 1 a.a. ~ 672 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SHC SH2-domain binding protein 1
Entrez Gene ID
79801
UniProt ID
Q8NEM2
Alternative Names
FLJ22009; MGC26900; PAL
Function
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.
Biological Process
Biological Process fibroblast growth factor receptor signaling pathwayISS:UniProtKB
Biological Process regulation of neural precursor cell proliferationISS:UniProtKB
Cellular Location
Midbody
Cytoplasm, cytoskeleton, spindle
Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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