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Rabbit Anti-SHCBP1 Monoclonal Antibody (SP11) (CBMAB-1456-YC)

Provided herein is a rabbit monoclonal antibody against Mouse SHCBP1. The antibody, clone SP11, can be used for immunoassay techniques, such as IP and WB.
See all SHCBP1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Human, Rat
Clone
SP11
Antibody Isotype
IgG
Application
IP, WB

Basic Information

Immunogen
Recombinant fragment within Mouse SHCBP1 aa 400 to the C-terminus.
Specificity
Mouse, Human, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SHC SH2-domain binding protein 1
Introduction
SHCBP1 is a protein that in humans is encoded by the SHCBP1 gene which has been shown to interact with SHC1.
Entrez Gene ID
Human79801
Mouse20419
Rat364648
UniProt ID
HumanQ8NEM2
MouseQ9Z179
RatA0A0G2K2J0
Alternative Names
SHC SH2 domain-binding protein 1; Protein expressed in Activated Lymphocytes
Function
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.
Biological Process
Biological Process fibroblast growth factor receptor signaling pathwayISS:UniProtKB
Biological Process regulation of neural precursor cell proliferationISS:UniProtKB
Cellular Location
Midbody
Cytoplasm, cytoskeleton, spindle
Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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