SHCBP1
SHCBP1 is a protein that in humans is encoded by the SHCBP1 gene which has been shown to interact with SHC1.
Full Name
SHC SH2-domain binding protein 1
Function
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.
Biological Process
Biological Process fibroblast growth factor receptor signaling pathwayISS:UniProtKB
Biological Process regulation of neural precursor cell proliferationISS:UniProtKB
Biological Process regulation of neural precursor cell proliferationISS:UniProtKB
Cellular Location
Midbody
Cytoplasm, cytoskeleton, spindle
Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis.
Cytoplasm, cytoskeleton, spindle
Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis.
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Anti-SHCBP1 antibodies
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Target: SHCBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G8
Application*: WB, E
Target: SHCBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Human, Rat
Clone: SP11
Application*: IP, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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