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SHCBP1

SHCBP1 is a protein that in humans is encoded by the SHCBP1 gene which has been shown to interact with SHC1.

Full Name

SHC SH2-domain binding protein 1

Function

May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.

Biological Process

Biological Process fibroblast growth factor receptor signaling pathwayISS:UniProtKB
Biological Process regulation of neural precursor cell proliferationISS:UniProtKB

Cellular Location

Midbody
Cytoplasm, cytoskeleton, spindle
Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis.

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Anti-SHCBP1 antibodies

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Mouse Anti-SHCBP1 Recombinant Antibody (1G8) (CBMAB-A8111-LY)

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Target: SHCBP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1G8

Application*: WB, E

Rabbit Anti-SHCBP1 Monoclonal Antibody (SP11) (CBMAB-1456-YC)

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Target: SHCBP1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Human, Rat

Clone: SP11

Application*: IP, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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