Mouse Anti-SHPK Recombinant Antibody (CBXC-2844) (CBMAB-C5858-CQ)

Name: Mouse Anti-SHPK Recombinant Antibody (CBXC-2844)
SKU: CBMAB-C5858-CQ
Rating: 5 (1 reviews)

See all SHPK antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXC-2844

Application

WB, IHC, IF, IHC-P

Immunogen

Full length human recombinant protein of human SHPK(NP_037408)

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Sedoheptulokinase

Introduction

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

Entrez Gene ID

23729

UniProt ID

Q9UHJ6

Alternative Names

Sedoheptulokinase; Carbohydrate Kinase-Like Protein; CARKL; SHK; Carbohydrate Kinase-Like; EC 2.7.1.14;

Function

Acts as a modulator of macrophage activation through control of glucose metabolism.

Biological Process

Biological Process carbohydrate metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to interleukin-13ISS:UniProtKB
Biological Process cellular response to interleukin-4ISS:UniProtKB
Biological Process cellular response to lipopolysaccharideManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process glycerol metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process pentose-phosphate shuntTAS:Reactome
Biological Process pentose-phosphate shunt, non-oxidative branchISS:UniProtKB
Biological Process phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of inflammatory responseISS:UniProtKB
Biological Process regulation of macrophage activationISS:UniProtKB

Cellular Location

Cytoplasm

Involvement in disease

Sedoheptulokinase deficiency (SHPKD):
An autosomal recessive metabolic disease characterized by increased urinary erythritol and sedoheptulose. Neonatal cholestasis, hypoglycemia, anemia, congenital arthrogryposis multiplex, multiple contractures and dysmorphisms have been reported in SHPKD patients, but the relationship of these features to the SHPKD is unclear.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-SHPK Recombinant Antibody (CBXC-2844)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-SHPK Recombinant Antibody (CBXS-5052) (CAT#: CBMAB-S2273-CQ)

Mouse Anti-SHPK Recombinant Antibody (CBXS-4853) (CAT#: CBMAB-S2076-CQ)

Rabbit Anti-SHPK Recombinant Antibody (EG481) (CAT#: CBMAB-EN545-LY)

Mouse Anti-SHPK Recombinant Antibody (3D7) (CAT#: CBMAB-C5894-LY)

Mouse Anti-SHPK Recombinant Antibody (CBXS-3976) (CAT#: CBMAB-S1239-CQ)

Mouse Anti-SHPK Recombinant Antibody (CBXS-4341) (CAT#: CBMAB-S1586-CQ)

Mouse Anti-SHPK Recombinant Antibody (CBXS-3955) (CAT#: CBMAB-S1218-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry