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Rat Anti-SIGLEC5 Recombinant Antibody (1RNM44N) (CBMAB-C0557-LY)

This product is antibody recognizes SIGLEC5. The antibody 1RNM44N immunoassay techniques such as: FC, ICC, IF, IHC-F.
See all SIGLEC5 antibodies
Published Data
Fig.1 Representative images of paraffin-embedded ulna/humerus joint interface (20X) stained with haematoxylin and eosi.
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Fig.2 The proliferation and differentiation of CD4+ T cells were evaluated via flow cytometry.
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Summary

Host Animal
Rat
Specificity
Mouse
Clone
1RNM44N
Antibody Isotype
IgG2a, κ
Application
FC, ICC, IF, IHC-F

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Sialic Acid Binding Ig Like Lectin 5
Introduction
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
Entrez Gene ID
83382
UniProt ID
Q920G3
Function
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Biological Process
Cell adhesion
Cellular Location
Membrane
Topology
Extracellular: 17-441
Helical: 442-462
Cytoplasmic: 463-551
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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