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Mouse Anti-SLC14A2 Recombinant Antibody (3E7) (CBMAB-A8170-LY)

The product is antibody recognizes SLC14A2. The antibody 3E7 immunoassay techniques such as: sELISA, ELISA.
See all SLC14A2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3E7
Antibody Isotype
IgG2a, κ
Application
sELISA, ELISA

Basic Information

Immunogen
SLC14A2 (NP_009094, 40 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
solute carrier family 14 (urea transporter), member 2
Introduction
In mammalian cells, urea is the chief end-product of nitrogen catabolism and plays an important role in the urinary concentration mechanism. Thus, the plasma membrane of erythrocytes and some renal epithelial cells exhibit an elevated urea permeability that is mediated by highly selective urea transporters. In mammals, 2 urea transporters have been identified: the renal tubular urea transporter, UT2, and the erythrocyte urea transporter, UT11 (SLC14A1; MIM 111000).[supplied by OMIM
Entrez Gene ID
8170
UniProt ID
Q15849
Alternative Names
FLJ16167; HUT2; MGC119566; MGC119567; UT-A2; UT2; UTA; UTR; hUT-A6
Function
Isoform 1
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism.
Isoform 2
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism.
Biological Process
Biological Process transmembrane transportTAS:Reactome
Biological Process urea transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process urea transportManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Apical cell membrane
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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