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Rabbit Anti-SLC14A2 Recombinant Antibody (CBXS-1611) (CBMAB-S4460-CQ)

This product is a rabbit antibody that recognizes SLC14A2. The antibody CBXS-1611 can be used for immunoassay techniques such as: WB, IP.
See all SLC14A2 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Human
Clone
CBXS-1611
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Specificity
Mouse, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 14 (urea transporter), member 2
Introduction
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.
Entrez Gene ID
Human8170
Mouse27411
UniProt ID
HumanQ15849
MouseQ8R4T9
Alternative Names
Solute Carrier Family 14 Member 2; Solute Carrier Family 14 (Urea Transporter), Member 2; Urea Transporter, Kidney; HUT2; UT2; Urea Transporter 2;
Function
Isoform 1
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism.
Isoform 2
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism.
Biological Process
Biological Process transmembrane transportTAS:Reactome
Biological Process urea transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process urea transportManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Apical cell membrane
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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