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Mouse Anti-SLC14A2 Recombinant Antibody (CBXS-3073) (CBMAB-S5818-CQ)

This product is a mouse antibody that recognizes SLC14A2. The antibody CBXS-3073 can be used for immunoassay techniques such as: ELISA.
See all SLC14A2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3073
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa40-129 from SLC14A2 (NP_009094) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 14 (urea transporter), member 2
Introduction
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.
Entrez Gene ID
8170
UniProt ID
Q15849
Alternative Names
Solute Carrier Family 14 Member 2; Solute Carrier Family 14 (Urea Transporter), Member 2; Urea Transporter, Kidney; HUT2; UT2; Urea Transporter 2;
Function
Isoform 1
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism.
Isoform 2
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism.
Biological Process
Biological Process transmembrane transportTAS:Reactome
Biological Process urea transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process urea transportManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Apical cell membrane
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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