Rabbit Anti-SLC25A12 Recombinant Antibody (
10B12) (V2LY-0725-LY1462)
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Positive WB detected in: U87 whole cell lysate, A549 whole cell lysate
All lanes: SLC25A12 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 75, 63 kDa
Observed band size: 72-80 kDa
Basic Information
| Application | Note |
| WB | 1:500-1:2,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (PubMed:11566871).
Biological Process aspartate transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process gluconeogenesisTAS:Reactome
Biological Process glutamate biosynthetic processIEA:Ensembl
Biological Process L-glutamate transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process malate-aspartate shuttleManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of glucose catabolic process to lactate via pyruvateIEA:Ensembl
Biological Process positive regulation of ATP biosynthetic processIEA:Ensembl
Biological Process positive regulation of glucose metabolic processIEA:Ensembl
Biological Process positive regulation of myelinationIEA:Ensembl
Biological Process response to calcium ionManual Assertion Based On ExperimentIDA:UniProtKB
A form of epileptic encephalopathy, a heterogeneous group of severe early-onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE39 is characterized by global hypomyelination of the central nervous system, with the gray matter appearing relatively unaffected. Inheritance is autosomal recessive.
Helical: 330-347
Mitochondrial matrix: 348-390
Helical: 391-410
Mitochondrial intermembrane: 411-433
Helical: 434-447
Mitochondrial matrix: 448-482
Helical: 483-502
Mitochondrial intermembrane: 503-521
Helical: 522-539
Mitochondrial matrix: 540-578
Helical: 579-598
Mitochondrial intermembrane: 599-678
10B12)?
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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