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Mouse Anti-SLC2A3 Recombinant Antibody (IHC585) (CBMAB-MA225-YC)

Provided herein is a Mouse monoclonal antibody against Solute Carrier Family 2 Member 3. The antibody can be used for immunoassay techniques, such as IHC. And it gave a positive signal in Embryonal Carcinoma and Yolk Sac Tumor.
See all SLC2A3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
IHC585
Application
IHC (1:100 - 1:200)

Basic Information

Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
Tris buffer pH 7.3 - 7.7, 1% BSA, < 0.1% Sodium Azide
Storage
Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Target

Full Name
Solute Carrier Family 2 Member 3
Introduction
Glucose transporter 3, also known as solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) is a protein that in humans is encoded by the SLC2A3gene. GLUT3 facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT3 is most known for its specific expression in neurons and has originally been designated as the neuronal GLUT. GLUT3 has been studied in other cell types with specific glucose requirements, including sperm, preimplantation embryos, circulating white blood cells and carcinoma cell lines.
Entrez Gene ID
6515
UniProt ID
P11169
Alternative Names
Solute Carrier Family 2 Member 3; Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3; Glucose Transporter Type 3, Brain; GLUT-3; GLUT3; Solute Carrier Family 2, Facilitated Glucose Transporter Member 3;
Function
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:9477959, PubMed:26176916).
Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (PubMed:9477959, PubMed:26176916).
Does not mediate fructose transport (PubMed:9477959, PubMed:26176916).
Biological Process
Biological Process carbohydrate metabolic process1 PublicationNAS:ProtInc
Biological Process dehydroascorbic acid transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process galactose transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process glucose importManual Assertion Based On ExperimentIBA:GO_Central
Biological Process glucose import across plasma membraneManual Assertion Based On ExperimentIGI:ARUK-UCL
Biological Process glucose transmembrane transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process L-ascorbic acid metabolic processTAS:Reactome
Biological Process monosaccharide transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process transport across blood-brain barrierManual Assertion Based On ExperimentIGI:ARUK-UCL
Cellular Location
Cell membrane
Perikaryon
Cell projection
Localized to densely spaced patches along neuronal processes.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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