Mouse Anti-SLC2A4 Recombinant Antibody (CBLG1-3109) (CBMAB-G6575-LY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process brown fat cell differentiationIEA:Ensembl
Biological Process carbohydrate metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cellular response to hypoxiaIEA:Ensembl
Biological Process cellular response to insulin stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cellular response to osmotic stressIEA:Ensembl
Biological Process cellular response to tumor necrosis factorIEA:Ensembl
Biological Process glucose homeostasisManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process glucose import1 PublicationNAS:BHF-UCL
Biological Process glucose import in response to insulin stimulusISS:UniProtKB
Biological Process glucose transmembrane transportISS:UniProtKB
Biological Process learning or memoryISS:ARUK-UCL
Biological Process long-term memoryISS:ARUK-UCL
Biological Process monosaccharide transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of brain-derived neurotrophic factor receptor signaling pathwayISS:ARUK-UCL
Biological Process regulation of synaptic vesicle budding from presynaptic endocytic zone membraneIEA:Ensembl
Biological Process response to ethanolIEA:Ensembl
Biological Process short-term memoryISS:ARUK-UCL
Biological Process transport across blood-brain barrier1 PublicationNAS:ARUK-UCL
Endomembrane system
Cytoplasm, perinuclear region
Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized (PubMed:8300557).
The dileucine internalization motif is critical for intracellular sequestration (PubMed:8300557).
Insulin stimulation induces translocation to the cell membrane (By similarity)
A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Palmitoylated (PubMed:28057756).
Palmitoylation by ZDHHC7 controls the insulin-dependent translocation of GLUT4 to the plasma membrane (PubMed:28057756).
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
SLC2A4 Matched Antibody Pair (1098) (CAT#: APMAB-1098LY)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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