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Mouse Anti-SLC30A5 Recombinant Antibody (2F10-2B8) (CBMAB-Z0700-WJ)

This product is a mouse antibody that recognizes SLC30A5. The antibody 2F10-2B8 can be used for immunoassay techniques such as: WB, IP, ELISA.
See all SLC30A5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2F10-2B8
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
solute carrier family 30 (zinc transporter), member 5
Introduction
SLC30A5 (solute carrier family 30 member 5) is a protein coding gene.
Entrez Gene ID
64924
UniProt ID
Q8TAD4
Alternative Names
ZnT5
Function
Zinc ion:proton antiporter mediating zinc entry into the lumen of organelles along the secretory pathway (PubMed:11904301, PubMed:15525635, PubMed:15994300, PubMed:19366695, PubMed:22529353).
By contributing to zinc ion homeostasis within the early secretory pathway regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (PubMed:15525635, PubMed:15994300, PubMed:16636052, PubMed:35525268).
Through the transport of zinc into secretory granules of pancreatic beta-cells, plays an important role in the storage and secretion of insulin (PubMed:11904301).
Isoform 2
Zinc ion:proton antiporter mediating influx and efflux of zinc at the plasma membrane.
Biological Process
Biological Process cellular zinc ion homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cobalt ion transportManual Assertion Based On ExperimentIDA:MGI
Biological Process insulin processingTAS:Reactome
Biological Process metal ion transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion import across plasma membraneIDA:UniProtKB
Biological Process zinc ion import into Golgi lumenManual Assertion Based On ExperimentIBA:GO_Central
Biological Process zinc ion import into organelleIDA:UniProtKB
Biological Process zinc ion transmembrane transportTAS:Reactome
Biological Process zinc ion transportManual Assertion Based On ExperimentIDA:MGI
PTM
Could homodimerize through the formation of dityrosine bonds upon oxidative stress.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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