Mouse Anti-SLC4A8 Recombinant Antibody (1G10) (CBMAB-A8248-LY)

Name: Mouse Anti-SLC4A8 Recombinant Antibody (1G10)
SKU: CBMAB-A8248-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1G10

Application

WB, ELISA

Immunogen

SLC4A8 (NP_004849, 187 a.a. ~ 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human, Mouse

Antibody Isotype

IgG3, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

solute carrier family 4, sodium bicarbonate cotransporter, member 8

Entrez Gene ID

Human	9498
Mouse	59033

UniProt ID

Human	Q2Y0W8
Mouse	Q8JZR6

Alternative Names

DKFZp761B2318; FLJ46462; NBC3

Function

Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3- exchange with a Na+:HCO3- stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3- from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3- into the cells. Also mediates lithium-dependent HCO3- cotransport. May be regulated by osmolarity.

Biological Process

Biological Process bicarbonate transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process chloride transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process modulation of chemical synaptic transmissionISS:ARUK-UCL
Biological Process positive regulation of synaptic vesicle exocytosisISS:ARUK-UCL
Biological Process regulation of intracellular pHManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process regulation of membrane potentialManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process sodium ion transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process transport across blood-brain barrier1 PublicationNAS:ARUK-UCL

Cellular Location

Membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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