Mouse Anti-SLU7 Recombinant Antibody (CBXS-2739) (CBMAB-S5490-CQ)

Name: Mouse Anti-SLU7 Recombinant Antibody (CBXS-2739)
SKU: CBMAB-S5490-CQ
Rating: 5 (1 reviews)

See all SLU7 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-2739

Application

ELISA, WB

Immunogen

Full length recombinant corresponding to aa1-586 from SLU7 (AAH10634) with GST tag

Specificity

Human

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SLU7 splicing factor homolog (S. cerevisiae)

Introduction

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions.

Entrez Gene ID

10569

UniProt ID

O95391

Alternative Names

SLU7 Homolog, Splicing Factor; Zinc Knuckle Motif Containing; HSlu7; SLU7 Splicing Factor Homolog (S. Cerevisiae); Pre-MRNA-Splicing Factor SLU7; SLU7 Splicing Factor Homolog; Step II Splicing Factor SLU7; Splicing Factor; 9G8;

Function

Required for pre-mRNA splicing as component of the spliceosome (PubMed:10197984, PubMed:28502770, PubMed:30705154).
Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.

Biological Process

Biological Process alternative mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process cellular response to heatManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA 3'-splice site recognitionManual Assertion Based On ExperimentIDA:HGNC-UCL
Biological Process mRNA splicing, via spliceosome1 PublicationIC:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentIDA:HGNC-UCL

Cellular Location

Nucleus
Nucleus speckle
Cytoplasm
Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-SLU7 Recombinant Antibody (CBXS-2739)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-SLU7 Recombinant Antibody (1D3-4A10) (CAT#: CBMAB-A8271-LY)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-2238) (CAT#: CBMAB-S5000-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-4296) (CAT#: CBMAB-S1542-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-2047) (CAT#: CBMAB-S4814-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-5856) (CAT#: CBMAB-S0710-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-2142) (CAT#: CBMAB-S4906-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-6180) (CAT#: CBMAB-S6467-CQ)

Rabbit Anti-SLU7 Recombinant Antibody (CBXS-1273) (CAT#: CBMAB-S4132-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-2244) (CAT#: CBMAB-S5006-CQ)

Mouse Anti-SLU7 Recombinant Antibody (CBXS-6181) (CAT#: CBMAB-S6469-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry