Mouse Anti-SMS Recombinant Antibody (CBXS-4748) (CBMAB-S1977-CQ)

Name: Mouse Anti-SMS Recombinant Antibody (CBXS-4748)
SKU: CBMAB-S1977-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-4748

Application

FC, IF, IHC-P, WB

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

spermine synthase

Introduction

This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

6611

UniProt ID

P52788

Alternative Names

Spermine Synthase; Spermidine Aminopropyltransferase; SPMSY; Snyder-Robinson X-Linked Mental Retardation Syndrome; EC 2.5.1.22; MRSR; SPS; SRS;

Function

Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).

Biological Process

Biological Process methionine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process polyamine metabolic processTAS:Reactome
Biological Process spermine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytosol
extracellular exosome

Involvement in disease

Intellectual developmental disorder, X-linked, syndromic, Snyder-Robinson type (MRXSSR):
An X-linked intellectual disability syndrome characterized by a collection of clinical features including facial asymmetry, marfanoid habitus, hypertonia, osteoporosis and unsteady gait.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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