SMS
The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. [provided by RefSeq]
Full Name
spermine synthase
Function
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
Biological Process
Biological Process methionine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process polyamine metabolic processTAS:Reactome
Biological Process spermine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process polyamine metabolic processTAS:Reactome
Biological Process spermine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
extracellular exosome
extracellular exosome
Involvement in disease
Intellectual developmental disorder, X-linked, syndromic, Snyder-Robinson type (MRXSSR):
An X-linked intellectual disability syndrome characterized by a collection of clinical features including facial asymmetry, marfanoid habitus, hypertonia, osteoporosis and unsteady gait.
An X-linked intellectual disability syndrome characterized by a collection of clinical features including facial asymmetry, marfanoid habitus, hypertonia, osteoporosis and unsteady gait.
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Anti-SMS antibodies
+ Filters
Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4748
Application*: F, IF, P, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G6
Application*: WB, E
Target: SMS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1634
Application*: WB, F
Target: SMS
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1633
Application*: WB, F, IF
Target: SMS
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5175
Application*: F, IF, P, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5166
Application*: F, IF, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat, Dog
Clone: CBXS-4824
Application*: WB, F, IH, IF, P
Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4639
Application*: F, IF, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4635
Application*: F, IF, P, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4185
Application*: F, IF, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4180
Application*: E, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3833
Application*: F, IF, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5766
Application*: F, IF, WB
Target: SMS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5738
Application*: F, IF, WB
Target: SMS
Sensitivity: 0.0097 ng/mL
Detection Range: 0.02-6 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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