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Mouse Anti-SMS Recombinant Antibody (CBXS-5738) (CBMAB-S0601-CQ)

This product is a mouse antibody that recognizes SMS. The antibody CBXS-5738 can be used for immunoassay techniques such as: FC, IF, WB.
See all SMS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5738
Antibody Isotype
IgG1
Application
FC, IF, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.29 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
spermine synthase
Introduction
This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
6611
UniProt ID
P52788
Alternative Names
Spermine Synthase; Spermidine Aminopropyltransferase; SPMSY; Snyder-Robinson X-Linked Mental Retardation Syndrome; EC 2.5.1.22; MRSR; SPS; SRS;
Function
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
Biological Process
Biological Process methionine metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process polyamine metabolic processTAS:Reactome
Biological Process spermine biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
extracellular exosome
Involvement in disease
Intellectual developmental disorder, X-linked, syndromic, Snyder-Robinson type (MRXSSR):
An X-linked intellectual disability syndrome characterized by a collection of clinical features including facial asymmetry, marfanoid habitus, hypertonia, osteoporosis and unsteady gait.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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