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Mouse Anti-SMU1 Recombinant Antibody (CBXS-0973) (CBMAB-S3881-CQ)

This product is a mouse antibody that recognizes SMU1. The antibody CBXS-0973 can be used for immunoassay techniques such as: ELISA, WB, IF, WB.
See all SMU1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0973
Antibody Isotype
IgG2b, κ
Application
ELISA, WB, IF, WB

Basic Information

Immunogen
SMU1 (AAH02876, 1 a.a.-513 a.a) Full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SMU1, DNA Replication Regulator And Spliceosomal Factor
Introduction
SMU1 (SMU1, DNA Replication Regulator And Spliceosomal Factor) is a Protein Coding gene. Diseases associated with SMU1 include Influenza. An important paralog of this gene is APAF1.
Entrez Gene ID
55234
UniProt ID
Q2TAY7
Alternative Names
SMU1, DNA Replication Regulator And Spliceosomal Factor; Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog; DNA Replication Regulator And Spliceosomal Factor; Functional Spliceosome-Associated Protein 57; Smu-1 Suppressor Of Mec-8 And Unc-52 Homolog (C. Elegans); Smu-1 Suppressor Of Mec-8 And Unc-52 Homolog;
Function
Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166).
Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity).
Required for normal accumulation of IK (PubMed:24945353).
Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
(Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Biological Process
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of alternative mRNA splicing, via spliceosomeISS:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Nucleus
Nucleus speckle
Colocalizes with SRSF1 in nuclear speckles.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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