Mouse Anti-SMU1 Recombinant Antibody (CBXS-2838) (CBMAB-S5588-CQ)

Name: Mouse Anti-SMU1 Recombinant Antibody (CBXS-2838)
SKU: CBMAB-S5588-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-2838

Application

ELISA, IF, WB

Immunogen

Full length recombinant corresponding to aa1-514 from human SMU1 (AAH02876) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SMU1, DNA Replication Regulator And Spliceosomal Factor

Introduction

SMU1 (SMU1, DNA Replication Regulator And Spliceosomal Factor) is a Protein Coding gene. Diseases associated with SMU1 include Influenza. An important paralog of this gene is APAF1.

Entrez Gene ID

55234

UniProt ID

Q2TAY7

Alternative Names

SMU1, DNA Replication Regulator And Spliceosomal Factor; Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog; DNA Replication Regulator And Spliceosomal Factor; Functional Spliceosome-Associated Protein 57; Smu-1 Suppressor Of Mec-8 And Unc-52 Homolog (C. Elegans); Smu-1 Suppressor Of Mec-8 And Unc-52 Homolog;

Function

Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166).
Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity).
Required for normal accumulation of IK (PubMed:24945353).
Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
(Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.

Biological Process

Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of alternative mRNA splicing, via spliceosomeISS:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Nucleus
Nucleus speckle
Colocalizes with SRSF1 in nuclear speckles.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Mouse Anti-SMU1 Recombinant Antibody (CBXS-0973) (CAT#: CBMAB-S3881-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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