SMU1

SMU1 (SMU1, DNA Replication Regulator And Spliceosomal Factor) is a protein coding gene. Diseases associated with SMU1 include Influenza. An important paralog of this gene is APAF1.
Full Name
SMU1, DNA Replication Regulator And Spliceosomal Factor
Function
Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166).
Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity).
Required for normal accumulation of IK (PubMed:24945353).
Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
(Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Biological Process
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of alternative mRNA splicing, via spliceosomeISS:UniProtKB
Biological Process RNA splicingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Nucleus
Nucleus speckle
Colocalizes with SRSF1 in nuclear speckles.
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Anti-SMU1 antibodies

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Target: SMU1
Host: Mouse
Specificity: Human
Clone: AQ26-ED8-22-11
Application*: IH, IF, WB
Target: SMU1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-2838
Application*: E, IF, WB
Target: SMU1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-0973
Application*: E, WB, IF, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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