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Mouse Anti-SND1 Recombinant Antibody (CBT1257) (V2LY-0625-LY2898)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT1257
Antibody Isotype
IgG
Application
WB, ELISA

Basic Information

Immunogen
Purified recombinant fragment of TudorSN (aa361-485) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
ELISA1:10,000
WB1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Buffer
BSA, Glycerol
Preservative
Sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Staphylococcal Nuclease And Tudor Domain Containing 1
Entrez Gene ID
27044
Function
Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:28546213, PubMed:18453631).
As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213).
Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934).
Plays a role in PIM1 regulation of MYB activity (PubMed:9809063).
Functions as a transcriptional coactivator for STAT5 (By similarity).
(Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).
Biological Process
Biological Process gene silencing by RNAIEA:InterPro
Biological Process miRNA catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process osteoblast differentiationManual Assertion Based On ExperimentHDA:UniProtKB
Biological Process regulation of cell cycle processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Melanosome
In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934).
Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
PTM
Phosphorylated by PIM1 in vitro.
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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