SND1

This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016]
Full Name
Staphylococcal Nuclease And Tudor Domain Containing 1
Function
Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:28546213, PubMed:18453631).
As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213).
Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934).
Plays a role in PIM1 regulation of MYB activity (PubMed:9809063).
Functions as a transcriptional coactivator for STAT5 (By similarity).
(Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).
Biological Process
Biological Process gene silencing by RNAIEA:InterPro
Biological Process miRNA catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process mRNA catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process osteoblast differentiationManual Assertion Based On ExperimentHDA:UniProtKB
Biological Process regulation of cell cycle processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Melanosome
In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934).
Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
PTM
Phosphorylated by PIM1 in vitro.
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Anti-SND1 antibodies

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Mouse Anti-SND1 Recombinant Antibody (2D7) (CBMAB-AO978LY)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D7
Application*: WB
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBXS-2458) (CBMAB-S5215-CQ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-2458
Application*: E, WB
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBXS-4502) (CBMAB-S1743-CQ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4502
Application*: WB
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBXS-4309) (CBMAB-S1554-CQ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4309
Application*: DB, WB
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBXS-3832) (CBMAB-S1102-CQ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXS-3832
Application*: IR, E, IF, IH, IP, WB
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBYJT-1678) (CBMAB-T0728-YJ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-1678
Application*: WB, IP, IF, P, E
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBYJT-1677) (CBMAB-T0727-YJ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Mouse
Clone: CBYJT-1677
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBYJT-1676) (CBMAB-T0726-YJ)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1676
Application*: WB, IP, IF, P, E
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBT1257) (V2LY-0625-LY2898)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT1257
Application*: WB, E
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CBT4047) (V2LY-0625-LY2222)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4047
Application*: WB
Datasheet SDS

Mouse Anti-SND1 Recombinant Antibody (CF403) (CBMAB-FT474LY)

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Target: SND1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF403
Application*: ELISA, IF, WB, IHC
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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