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Mouse Anti-SNPH Recombinant Antibody (CBXS-4777) (CBMAB-S2004-CQ)

This product is a mouse antibody that recognizes SNPH. The antibody CBXS-4777 can be used for immunoassay techniques such as: ELISA, WB.
See all SNPH antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4777
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
SNPH (NP_055538.2, 251 a.a.-348 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
syntaphilin
Introduction
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
9751
UniProt ID
O15079
Alternative Names
Syntaphilin; KIAA0374;
Function
Inhibits SNARE complex formation by absorbing free syntaxin-1.
Biological Process
Biological Process neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neurotransmitter secretion1 PublicationNAS:UniProtKB
Biological Process synaptic vesicle docking1 PublicationNAS:UniProtKB
Cellular Location
Membrane
Synapse, synaptosome
Topology
Helical: 425-444
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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