SNPH

Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. [provided by RefSeq]

Full Name

syntaphilin

Function

Inhibits SNARE complex formation by absorbing free syntaxin-1.

Biological Process

Biological Process neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neurotransmitter secretion1 PublicationNAS:UniProtKB
Biological Process synaptic vesicle docking1 PublicationNAS:UniProtKB

Cellular Location

Membrane
Synapse, synaptosome

Topology

Helical: 425-444

Anti-SNPH antibodies

Mouse Anti-SNPH Recombinant Antibody (CBXS-4777) (CBMAB-S2004-CQ)

Datasheet

SDS

Target: SNPH

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4777

Application*: E, WB

Mouse Anti-SNPH Recombinant Antibody (CBXS-5516) (CBMAB-S2724-CQ)

Datasheet

SDS

Target: SNPH

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Rat, Mouse

Clone: CBXS-5516

Application*: WB, E

Rabbit Anti-SNPH Recombinant Antibody (CBXS-1371) (CBMAB-S4229-CQ)

Datasheet

SDS

Target: SNPH

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBXS-1371

Application*: WB, P

Mouse Anti-SNPH Recombinant Antibody (3B6) (CBMAB-A8422-LY)

Datasheet

SDS

Target: SNPH

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3B6

Application*: WB, E

Rabbit Anti-SNPH Monoclonal Antibody (EPR14115(2)) (CBMAB-1475-YC)

Datasheet

SDS

Target: SNPH

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EPR14115(2)

Application*: P, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)