Mouse Anti-SNPH Recombinant Antibody (CBXS-5516) (CBMAB-S2724-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBXS-5516
Application
WB, ELISA
Specificity
Human, Rat, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
syntaphilin
Introduction
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.
Entrez Gene ID
Human9751
Mouse241727
Rat296267
UniProt ID
HumanO15079
MouseQ80U23
RatB5DF41
Alternative Names
Syntaphilin; KIAA0374;
Function
Inhibits SNARE complex formation by absorbing free syntaxin-1.
Biological Process
Biological Process neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neurotransmitter secretion1 PublicationNAS:UniProtKB
Biological Process synaptic vesicle docking1 PublicationNAS:UniProtKB
Cellular Location
Membrane
Synapse, synaptosome
Topology
Helical: 425-444
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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