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Mouse Anti-SNU13 Recombinant Antibody (5C5) (CBMAB-N2440-WJ)

This product is a Mouse antibody that recognizes SNU13. The antibody 5C5 can be used for immunoassay techniques such as: ELISA.
See all SNU13 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
5C5
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
Introduction
SNU13 (Small Nuclear Ribonucleoprotein 13) is a Protein Coding gene. Diseases associated with SNU13 include Sperm-Specific Antigen 1. Among its related pathways are mRNA Splicing - Major Pathway and rRNA processing in the nucleus and cytosol.
Entrez Gene ID
UniProt ID
Alternative Names
15.5K, FA-1, FA1, NHP2L1, NHPX, OTK27, SNRNP15-5, SPAG12, SSFA1
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28781166).
Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed:10545122, PubMed:17412961).
The protein undergoes a conformational change upon RNA-binding (PubMed:17412961).
Biological Process
Biological Process box C/D snoRNP assemblyIEA:Ensembl
Biological Process maturation of LSU-rRNAManual Assertion Based On ExperimentIBA:GO_Central
Biological Process maturation of SSU-rRNAManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process single fertilizationIEA:Ensembl
Cellular Location
Nucleus
Nucleus, nucleolus
Concentrated in the dense fibrillar component of the nucleolus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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