SNU13

Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.
Full Name
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28781166).
Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed:10545122, PubMed:17412961).
The protein undergoes a conformational change upon RNA-binding (PubMed:17412961).
Biological Process
Biological Process box C/D snoRNP assemblyIEA:Ensembl
Biological Process maturation of LSU-rRNAManual Assertion Based On ExperimentIBA:GO_Central
Biological Process maturation of SSU-rRNAManual Assertion Based On ExperimentIBA:GO_Central
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process single fertilizationIEA:Ensembl
Cellular Location
Nucleus
Nucleus, nucleolus
Concentrated in the dense fibrillar component of the nucleolus.
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Anti-SNU13 antibodies

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Mouse Anti-SNU13 Recombinant Antibody (5C5) (CBMAB-A5973-LY)

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Target: SNU13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5C5
Application*: SE, E
Datasheet SDS

Rabbit Anti-SNU13 Recombinant Antibody (CBWJN-1404) (CBMAB-N2441-WJ)

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Target: SNU13
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBWJN-1404
Application*: WB, IP, P, F, IC
Datasheet SDS

Mouse Anti-SNU13 Recombinant Antibody (5C5) (CBMAB-N2440-WJ)

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Target: SNU13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5C5
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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