Rabbit Anti-SPINK1 Recombinant Antibody (CBXS-1441) (CBMAB-S4299-CQ)
Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity).
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Biological Process negative regulation of calcium ion importIEA:Ensembl
Biological Process negative regulation of nitric oxide mediated signal transductionIEA:Ensembl
Biological Process negative regulation of peptidyl-tyrosine phosphorylationIEA:Ensembl
Biological Process negative regulation of serine-type endopeptidase activityIEA:Ensembl
Biological Process nitric oxide mediated signal transductionIEA:Ensembl
Biological Process peptidyl-tyrosine phosphorylationIEA:Ensembl
Biological Process positive regulation of cytosolic calcium ion concentrationIEA:Ensembl
Biological Process positive regulation of epithelial cell proliferationIEA:Ensembl
Biological Process positive regulation of pancreatic juice secretionIEA:Ensembl
Biological Process positive regulation of peptide hormone secretionIEA:Ensembl
Biological Process regulation of acrosome reactionIEA:Ensembl
Biological Process regulation of store-operated calcium entryIEA:Ensembl
Biological Process response to ethanolIEA:Ensembl
Biological Process response to nutrient levelsIEA:Ensembl
Biological Process sperm capacitationIEA:Ensembl
A disease characterized by pancreas inflammation, permanent destruction of the pancreatic parenchyma, maldigestion, and severe abdominal pain attacks.
Tropical calcific pancreatitis (TCP):
Idiopathic, juvenile, nonalcoholic form of chronic pancreatitis widely prevalent in several tropical countries. It can be associated with fibrocalculous pancreatic diabetes (FCPD) depending on both environmental and genetic factors. TCP differs from alcoholic pancreatitis by a much younger age of onset, pancreatic calcification, a high incidence of insulin dependent but ketosis resistant diabetes mellitus, and an exceptionally high incidence of pancreatic cancer.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
SPINK1 Matched Antibody Pair (1132) (CAT#: APMAB-1132LY)
Related Products
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Mouse Anti-SPINK1 Recombinant Antibody (CBYJT-1680) (CAT#: CBMAB-T0730-YJ)
Mouse Anti-SPINK1 Recombinant Antibody (1B12) (CAT#: CBMAB-A8538-LY)
SPINK1 Matched Antibody Pair (1132) (CAT#: APMAB-1132LY)
Rabbit Anti-SPINK1 Recombinant Antibody (SP166) (CAT#: CBMAB-S6590-CQ)
Mouse Anti-SPINK1 Recombinant Antibody (CBXS-1950) (CAT#: CBMAB-S4727-CQ)
Rabbit Anti-SPINK1 Recombinant Antibody (CBXS-1330) (CAT#: CBMAB-S4188-CQ)
Mouse Anti-SPINK1 Recombinant Antibody (CBXS-3191) (CAT#: CBMAB-S5932-CQ)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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