Mouse Anti-SRSF5 Recombinant Antibody (CBXS-0721) (CBMAB-S3654-CQ)

Name: Mouse Anti-SRSF5 Recombinant Antibody (CBXS-0721)
SKU: CBMAB-S3654-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-0721

Application

S-ELISA, IHC-P, ELISA, WB, IF, WB

Immunogen

SFRS17A (NP_005079, 53 a.a.-156 a.a) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Serine And Arginine Rich Splicing Factor 5

Introduction

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

6430

UniProt ID

Q13243

Alternative Names

Serine And Arginine Rich Splicing Factor 5; Splicing Factor, Arginine/Serine-Rich 5; Serine/Arginine-Rich Splicing Factor 5; Pre-MRNA-Splicing Factor SRP40; Delayed-Early Protein HRS; SR Splicing Factor 5; SFRS5; SRP40; HRS;

Function

Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.

Biological Process

Biological Process cellular response to insulin stimulusIEA:Ensembl
Biological Process liver regenerationIEA:Ensembl
Biological Process mRNA processingManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA splice site selectionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of RNA splicingIEA:Ensembl
Biological Process regulation of cell cycleIEA:Ensembl

Cellular Location

Nucleus

PTM

Extensively phosphorylated on serine residues in the RS domain.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-SRSF5 Recombinant Antibody (CBXS-3757) (CAT#: CBMAB-S1030-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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