Mouse Anti-STAMBPL1 Recombinant Antibody (CBXS-3543) (CBMAB-S6272-CQ)

Name: Mouse Anti-STAMBPL1 Recombinant Antibody (CBXS-3543)
SKU: CBMAB-S6272-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-3543

Application

Dot, WB

Immunogen

Partial recombinant sequence from human STAMBPL1

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 1% BSA

Preservative

0.05% sodium azide

Concentration

0.1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

STAM Binding Protein Like 1

Introduction

STAMBPL1 (STAM Binding Protein Like 1) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Deubiquitination. Gene Ontology (GO) annotations related to this gene include peptidase activity and metallopeptidase activity. An important paralog of this gene is STAMBP.Zinc metalloprotease that specifically cleaves Lys-63-linked polyubiquitin chains. Does not cleave Lys-48-linked polyubiquitin chains.

Entrez Gene ID

57559

UniProt ID

Q96FJ0

Alternative Names

ALMalpha; AMSH-FP; AMSH-LP; bA399O19.2

Function

Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains (PubMed:18758443, PubMed:35114100).
Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex (PubMed:35114100).
Does not cleave 'Lys-48'-linked polyubiquitin chains (PubMed:18758443).

Biological Process

Biological Process protein deubiquitinationTAS:Reactome
Biological Process protein K63-linked deubiquitinationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytosol
endosome
membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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