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Mouse Anti-STAMBPL1 Recombinant Antibody (CBXS-4253) (CBMAB-S1505-CQ)

This product is a mouse antibody that recognizes STAMBPL1. The antibody CBXS-4253 can be used for immunoassay techniques such as: Dot, ICC, WB.
See all STAMBPL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4253
Antibody Isotype
IgG1
Application
Dot, ICC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
STAM Binding Protein Like 1
Introduction
STAMBPL1 (STAM Binding Protein Like 1) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Deubiquitination. Gene Ontology (GO) annotations related to this gene include peptidase activity and metallopeptidase activity. An important paralog of this gene is STAMBP.Zinc metalloprotease that specifically cleaves Lys-63-linked polyubiquitin chains. Does not cleave Lys-48-linked polyubiquitin chains.
Entrez Gene ID
57559
UniProt ID
Q96FJ0
Alternative Names
ALMalpha; AMSH-FP; AMSH-LP; bA399O19.2
Function
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains (PubMed:18758443, PubMed:35114100).
Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex (PubMed:35114100).
Does not cleave 'Lys-48'-linked polyubiquitin chains (PubMed:18758443).
Biological Process
Biological Process protein deubiquitinationTAS:Reactome
Biological Process protein K63-linked deubiquitinationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
endosome
membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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