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Mouse Anti-STX12 Recombinant Antibody (3B9) (CBMAB-A8743-LY)

The product is antibody recognizes STX12. The antibody 3B9 immunoassay techniques such as: WB, ELISA.
See all STX12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3B9
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
STX12 (NP_803173, 108 a.a. ~ 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
syntaxin 12
Entrez Gene ID
23673
UniProt ID
Q86Y82
Alternative Names
MGC51957; STX13; STX14
Function
SNARE promoting fusion of transport vesicles with target membranes. Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
Biological Process
Biological Process autophagosome assemblyManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process cholesterol effluxManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process endocytic recyclingISS:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein stabilizationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endosome membrane
Golgi apparatus membrane
Endomembrane system
Early endosome membrane
Recycling endosome membrane
Topology
Cytoplasmic: 2-248
Helical: 249-269
Vesicular: 270-276
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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