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Mouse Anti-STX2 Recombinant Antibody (CBMJV-0251) (CBMAB-V208-0267-WJ)


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Summary

Host Animal
Mouse
Specificity
E. coli
Clone
CBMJV-0251
Antibody Isotype
IgG1
Application
FuncS, WB

Basic Information

Specificity
E. coli
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% BSA
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
STX2
Introduction
Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named after Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. The most common sources for Shiga toxin are the bacteria S. dysenteriae and the shigatoxigenic serotypes of Escherichia coli (STEC), which includes serotypes O157:H7, and O104:H4.
Alternative Names
Shiga toxin 2; STX2
Function
Essential for epithelial morphogenesis. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.
Biological Process
Biological Process acrosome reactionISS:HGNC-UCL
Biological Process animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cell differentiationIEA:InterPro
Biological Process cellular response to oxidative stressManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cornified envelope assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ectoderm developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process synaptic vesicle fusion to presynaptic active zone membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-264
Helical: 265-288
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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