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STX2

Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages. The toxins are named after Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. The most common sources for Shiga toxin are the bacteria S. dysenteriae and the shigatoxigenic serotypes of Escherichia coli (STEC), which includes serotypes O157:H7, and O104:H4.
Full Name
STX2
Function
Essential for epithelial morphogenesis. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.
Biological Process
Biological Process acrosome reactionISS:HGNC-UCL
Biological Process animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cell differentiationIEA:InterPro
Biological Process cellular response to oxidative stressManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cornified envelope assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ectoderm developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process synaptic vesicle fusion to presynaptic active zone membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-264
Helical: 265-288
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Anti-STX2 antibodies

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STX2 Matched Antibody Pair (1163) (APMAB-1163LY)

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Target: STX2
Specificity: Human
Datasheet SDS

Mouse Anti-STX2 Recombinant Antibody (CBMJV-0251) (CBMAB-V208-0267-WJ)

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Target: STX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: E. coli
Clone: CBMJV-0251
Application*: FN, WB
Datasheet SDS

Mouse Anti-STX2 Recombinant Antibody (CBXS-2015) (CBMAB-S4782-CQ)

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Target: STX2
Host: Mouse
Specificity: Human
Clone: CBXS-2015
Application*: WB, IP, IF, E
Datasheet SDS

Rat Anti-STX2 Recombinant Antibody (CBXS-4699) (CBMAB-S1931-CQ)

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Target: STX2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-4699
Application*: C, WB
Datasheet SDS

Mouse Anti-STX2 Recombinant Antibody (CBFYE-1659) (CBMAB-E2328-FY)

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Target: STX2
Host: Mouse
Specificity: Human
Clone: CBFYE-1659
Application*: WB, IC, P, C, E
Datasheet SDS

Rat Anti-STX2 (AA 1-189) Recombinant Antibody (CBFYE-1658) (CBMAB-E2327-FY)

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Target: STX2
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYE-1658
Application*: WB, IH
Datasheet SDS

Rat Anti-STX2 (AA 1-188) Recombinant Antibody (CBFYE-1657) (CBMAB-E2326-FY)

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Target: STX2
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1657
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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