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Rat Anti-STX2 (AA 1-189) Recombinant Antibody (CBFYE-1658) (CBMAB-E2327-FY)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYE-1658
Antibody Isotype
IgG2a
Application
WB, IHC

Basic Information

Immunogen
E.coli-derived recombinant mouse Epimorphin/Syntaxin 2, Met1-Arg189
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-189

Target

Full Name
STX2
Introduction
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation.
Entrez Gene ID
13852
UniProt ID
Q80W45
Alternative Names
Epim; Syn-2; repro34; AW538950; G1-536-1
Function
Essential for epithelial morphogenesis. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.
Biological Process
Biological Process acrosome reactionISS:HGNC-UCL
Biological Process animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cell differentiationIEA:InterPro
Biological Process cellular response to oxidative stressManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cornified envelope assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process ectoderm developmentManual Assertion Based On ExperimentTAS:ProtInc
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process synaptic vesicle fusion to presynaptic active zone membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Topology
Cytoplasmic: 1-264
Helical: 265-288
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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