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Mouse Anti-STX6 (AA 1-25) Recombinant Antibody (CBXS-3215) (CBMAB-S5956-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBXS-3215
Application
IP, WB
Immunogen
Recombinant rat syntaxin 6
Specificity
Hamster, Human, Mouse, Rat
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2, 50% glycerol
Preservative
0.09% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-25
More Infomation

Target

Full Name
Syntaxin 6
Introduction
STX6 (Syntaxin 6) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling and wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF). Gene Ontology (GO) annotations related to this gene include syntaxin binding and SNAP receptor activity. An important paralog of this gene is STX10.Involved in intracellular vesicle trafficking.
Entrez Gene ID
Hamster100753913
Mouse58244
Rat60562
Human10228
UniProt ID
HamsterA0A3Q0CSL3
MouseQ9JKK1
RatQ63635
HumanO43752
Alternative Names
Syntaxin 6
Function
SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.
Biological Process
Biological Process endocytic recyclingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process Golgi vesicle transportIEA:InterPro
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle to endosome fusionIEA:Ensembl
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIPI:UniProtKB
Cellular Location
Golgi apparatus membrane
Golgi apparatus, trans-Golgi network membrane
Recycling endosome membrane
Topology
Cytoplasmic: 2-234
Helical: 235-255
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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