STX6
STX6 (Syntaxin 6) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling and wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF). Gene Ontology (GO) annotations related to this gene include syntaxin binding and SNAP receptor activity. An important paralog of this gene is STX10.Involved in intracellular vesicle trafficking.
Full Name
Syntaxin 6
Function
SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.
Biological Process
Biological Process endocytic recyclingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process Golgi vesicle transportIEA:InterPro
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle to endosome fusionIEA:Ensembl
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIPI:UniProtKB
Biological Process Golgi vesicle transportIEA:InterPro
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle to endosome fusionIEA:Ensembl
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIPI:UniProtKB
Cellular Location
Golgi apparatus membrane
Golgi apparatus, trans-Golgi network membrane
Recycling endosome membrane
Golgi apparatus, trans-Golgi network membrane
Recycling endosome membrane
Topology
Cytoplasmic: 2-234
Helical: 235-255
Helical: 235-255
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Anti-STX6 antibodies
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Target: STX6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1G2
Application*: WB, E
Target: STX6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXS-6152
Application*: IC, IF, IP, WB
Target: STX6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Hamster, Human, Mouse, Rat
Clone: CBXS-3215
Application*: IP, WB
Target: STX6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1228
Application*: WB, IP, P, IF
Target: STX6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBXS-0833
Application*: IP, WB
Target: STX6
Host: Rabbit
Specificity: Human, Mouse, Rat
Clone: CBXS-0832
Application*: WB, IP, IF
Target: STX6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXS-4829
Application*: WB, IF, IP
Target: STX6
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBXS-4404
Application*: E, WB, IH
Target: STX6
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4158
Application*: E, IF, WB
Target: STX6
Host: Rabbit
Specificity: Human, Mouse, Rat
Clone: CBXS-5996
Application*: WB, IP, IF
Target: STX6
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBXS-5904
Application*: IC, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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