Mouse Anti-STX6 Recombinant Antibody (1G2) (CBMAB-A8751-LY)

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
1G2
Application
WB, ELISA
Immunogen
STX6 (AAH09944.1, 1 a.a. ~ 255 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Syntaxin 6
Entrez Gene ID
UniProt ID
Function
SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.
Biological Process
Biological Process endocytic recyclingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process Golgi vesicle transportIEA:InterPro
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process synaptic vesicle to endosome fusionIEA:Ensembl
Biological Process vesicle dockingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process vesicle fusionManual Assertion Based On ExperimentIPI:UniProtKB
Cellular Location
Golgi apparatus membrane
Golgi apparatus, trans-Golgi network membrane
Recycling endosome membrane
Topology
Cytoplasmic: 2-234
Helical: 235-255
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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